Immunogenic cell surface proteins of helicobacter pylori
Patenditaotlus: Immunogenic cell surface proteins of helicobacter pylori ; Omanikud: NordicBio AB; Autorid: FirstName_703221 LastName_703221, Ljungh, Asa; ; Nilsson, Ingrid; ; Wadstrom, Torkel; ; Prioriteedi number: 0101030-5; Prioriteedi kuupäev: 23.03.2001.
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Patenditaotlus
Immunogenic cell surface proteins of helicobacter pylori
Immunogenic cell surface proteins of helicobacter pylori
A method of identifying immunogenic Helicobacter pylori-specific surface proteins binding specifically to polysulphated molecules, is described. Further, a Helicobacter pylori-specific surface protein product, and a protein contained therein, binding specifically to polysulphated molecules are disclosed. Examples of such proteins are a protein having a MW of 30 (31.3) kDa, a (pI) of 9.3 (9.1) and comprising SEQ ID NO: 1 and/or SEQ ID NO: 2; a protein having a MW of 26 (27.7), a pI of 9.1-9.3 (9.0) and comprising SEQ ID NO: 4; or a protein having a MW of 25 (28.7), a pI of 9.0 (8.8) and comprising SEQ ID NO: 5. Additionally, use of a protein or protein product of the invention as a diagnostic antigen and as a component in a vaccine against H. pylori infection, as well as an immunoassay and a vaccine composition against a H. pylori infection, are described.
A method of identifying immunogenic Helicobacter pylori-specific surface proteins binding specifically to polysulphated molecules, is described. Further, a Helicobacter pylori-specific surface protein product, and a protein contained therein, binding specifically to polysulphated molecules are disclosed. Examples of such proteins are a protein having a MW of 30 (31.3) kDa, a (pI) of 9.3 (9.1) and comprising SEQ ID NO: 1 and/or SEQ ID NO: 2; a protein having a MW of 26 (27.7), a pI of 9.1-9.3 (9.0) and comprising SEQ ID NO: 4; or a protein having a MW of 25 (28.7), a pI of 9.0 (8.8) and comprising SEQ ID NO: 5. Additionally, use of a protein or protein product of the invention as a diagnostic antigen and as a component in a vaccine against H. pylori infection, as well as an immunoassay and a vaccine composition against a H. pylori infection, are described.
  • NordicBio AB
Prioriteeditaotlus
23.03.2001
0101030-5
Rahvusvaheline (IPC)
C07K 14/205, G01N 33/569, A61K 39/106, C12P 021/06
ROOTSI
Rootsi Kuningriik
Kaitstud
Järgnevad taotlused (2)
KuupäevNumberPatendiametRiikURLFailStaatus
20.03.2002PCT/SE02/0535RootsiRootsi KuningriikKaitstud
4.02.200420040115767USPTOAmeerika Ühendriigidappft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-Kaitstud